How to add ref attributes to content?

Is there any way to handle ref attributes for the <a> tag in markup?
I need to create a no follow in my content file links, but don’t see any native way to do this.

I read that, and as I understand the _markup/render-link.html will use global settings, will this apply to all links when used or just with the specific name modifier?

The templates in the render-*.html will apply to all elements, in your case all links (using the render-link.html file), withing the content directory.